Identifying and tracking individual particles within a dense sample can be a challenge, especially in 3D. One approach for circumventing this has been to fluorescently label only the core or center of each particle, providing a clear separation between the observable particle centers. However, the colloidal chemistry required to achieve this has not been trivial. Using an innovative technique, we can produce bulk quantities of micrometer-sized fluorescently-labelled core-shell particles, without the need for complex organic chemistry.
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- M.T. Elsesser, A.D. Hollingsworth, K.V. Edmond, and D.J. Pine, Langmuir 27, 917 (2010)