Core-shell particles

Identifying and tracking individual particles within a dense sample can be a challenge, especially in 3D.  One approach for circumventing this has been to fluorescently label only the core or center of each particle, providing a clear separation between the observable particle centers.  However, the colloidal chemistry required to achieve this has not been trivial.  Using an innovative technique, we can produce bulk quantities of micrometer-sized fluorescently-labelled core-shell particles, without the need for complex organic chemistry.


  • R.P.A. Dullens, Soft Matter 2, 805 (2006)
  • M.T. Elsesser, A.D. Hollingsworth, K.V. Edmond, and D.J. Pine, Langmuir 27, 917 (2010)